NEURON ON: A Bioactive Moringa Oil Targeting Oxidative Stress and Silent Synapses in Neurological Disorders Including Epilepsy

Recent research into neuronal regeneration for epilepsy has focused on silent, or passive, synapses— synaptic junctions that are anatomically present but electrically inactive. These synapses may serve as potential sites for reactivation and neuronal recovery, especially following injury or disease. "NEURON ON," a novel bioactive moringa oil formulation enriched with CBD and delivered via exogenous exosomes, aims to reduce oxidative stress and reawaken silent synapses. In a proof-of-concept trial, 243 patients with epilepsy (ages 25–75) received personalized sublingual doses of NEURON ON. The oxidative stress coefficient (OSC) was measured using the LONGLIFE OXY-LORD (LLOL) calculator. Results demonstrated that 198 participants (81.48%) showed a 50% reduction in OSC, corresponding to a 90% oxidative stress relief rate. Additionally, patients exhibited an average 12% reduction in estimated biological age. These findings suggest that NEURON ON may promote neuronal regeneration by forming a melanin-like lipid interface that facilitates connectivity among low-activity neurons. Given these outcomes, EEG evaluations are recommended to validate functional neural recovery. NEURON ON holds promise as a personalized oxidative stress-reducing therapy for epilepsy and other oxidative pathologies affecting neuronal connectivity.

Authors

Institutions

Publication Details

Journal
Neurology and Neuroscience
Published
2025-08-20
DOI
https://doi.org/10.33425/2692-7918.1099
Primary Topic
Moringa oleifera research and applications
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

NEURON ON: A Bioactive Moringa Oil Targeting Oxidative Stress and Silent Synapses in Neurological Disorders Including Epilepsy

Anna Carrasco, L Cruz-Rodriguez, Emili Martı́nez, Carmen Gallo García et al.
Neurology and Neuroscience
Moringa oleifera research and applications
article

NEURON ON: A Bioactive Moringa Oil Targeting Oxidative Stress and Silent Synapses in Neurological Disorders Including Epilepsy

Anna Carrasco, L Cruz-Rodriguez, Emili Martı́nez, Carmen Gallo García, A Angomas, M Valle-Orta, I Rosales-Castro, EA Dans
article en

Abstract

Recent research into neuronal regeneration for epilepsy has focused on silent, or passive, synapses— synaptic junctions that are anatomically present but electrically inactive. These synapses may serve as potential sites for reactivation and neuronal recovery, especially following injury or disease. "NEURON ON," a novel bioactive moringa oil formulation enriched with CBD and delivered via exogenous exosomes, aims to reduce oxidative stress and reawaken silent synapses. In a proof-of-concept trial, 243 patients with epilepsy (ages 25–75) received personalized sublingual doses of NEURON ON. The oxidative stress coefficient (OSC) was measured using the LONGLIFE OXY-LORD (LLOL) calculator. Results demonstrated that 198 participants (81.48%) showed a 50% reduction in OSC, corresponding to a 90% oxidative stress relief rate. Additionally, patients exhibited an average 12% reduction in estimated biological age. These findings suggest that NEURON ON may promote neuronal regeneration by forming a melanin-like lipid interface that facilitates connectivity among low-activity neurons. Given these outcomes, EEG evaluations are recommended to validate functional neural recovery. NEURON ON holds promise as a personalized oxidative stress-reducing therapy for epilepsy and other oxidative pathologies affecting neuronal connectivity.

Neurology and NeuroscienceVol. 6(5)
Hotel Dieu Hospital (CA), Kendall College (US), Moffitt Cancer Center (US), University of Alabama at Birmingham (US), Pain Management Institute (US), Applied Graphene Materials (United Kingdom) (GB), University of Tampa (US)
Openalex Percentile: Top 84%
Moringa oleifera research and applications
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

NEURON ON: A Bioactive Moringa Oil Targeting Oxidative Stress and Silent Synapses in Neurological Disorders Including Epilepsy — Anna Carrasco, L Cruz-Rodriguez, et al. · Neurology and Neuroscience (2025) | TGRS Research Map | TGRS