scmorph: a Python package for analysing single-cell morphological profiles

scmorph is a Python package to analyse single-cell data from imaging data of cell populations, specifically morphological profiling experiments, which generate large tabular data.scmorph combines domain-specific methods such as single-cell hit calling and batch correction with the versatile and scalable scverse tools to offer feature selection, dimensionality reduction, and more.Overall, scmorph brings together a host of single-cell morphological profiling methods, making it applicable for a wide range of experimental designs and workflows.

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Publication Details

Journal
The Journal of Open Source Software
Published
2025-08-22
DOI
https://doi.org/10.21105/joss.08324
Citations
3
Primary Topic
Single-cell and spatial transcriptomics
Type
article
Field-Weighted Citation Impact
2.42

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article

scmorph: a Python package for analysing single-cell morphological profiles

Ava Khamseh, Sjoerd Viktor Beentjes, Hugh Warden, Jesko Wagner
3 citations
The Journal of Open Source Software
Single-cell and spatial transcriptomics
2.42
article

scmorph: a Python package for analysing single-cell morphological profiles

Ava Khamseh, Sjoerd Viktor Beentjes, Hugh Warden, Jesko Wagner
article en
3 citations

Abstract

scmorph is a Python package to analyse single-cell data from imaging data of cell populations, specifically morphological profiling experiments, which generate large tabular data.scmorph combines domain-specific methods such as single-cell hit calling and batch correction with the versatile and scalable scverse tools to offer feature selection, dimensionality reduction, and more.Overall, scmorph brings together a host of single-cell morphological profiling methods, making it applicable for a wide range of experimental designs and workflows.

The Journal of Open Source SoftwareVol. 10(112)
Maxwell Institute for Mathematical Sciences (GB), Institute of Genetics and Cancer (GB), University of Edinburgh (GB)
Medical Research Council
Openalex Percentile: Top 10%
Single-cell and spatial transcriptomics
2.42
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scmorph: a Python package for analysing single-cell morphological profiles — Ava Khamseh, Sjoerd Viktor Beentjes, et al. · The Journal of Open Source Software (2025) | TGRS Research Map | TGRS