Clinical and prognostic significance of m6A hypomethylation and IGF2BP3 overexpression in gastric cancer: an integrated epigenomic-transcriptomic analysis
This study establishes m6A methylation dysregulation as a critical mechanism in GC pathogenesis and identifies IGF2BP3 as both a potential therapeutic target and a prognostic biomarker in GC.
Authors
- Youwei Kou (ORCID: https://orcid.org/0000-0001-8974-3828)
- Xiangchen Hu
- Yujing Huang (ORCID: https://orcid.org/0000-0001-8292-8002)
- Zhe Wang (ORCID: https://orcid.org/0000-0002-4950-9954)
Institutions
- China Medical University (CN)
Publication Details
- Journal
- Human Genomics
- Published
- 2025-08-22
- DOI
- https://doi.org/10.1186/s40246-025-00802-0
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- China Medical University
- Shengjing Hospital