In Vitro Analysis of Hyaluronidase Degradation of Commercial Hyaluronic Acid Fillers: Considerations in Lip Augmentation

HA fillers vary in their susceptibility to hyaluronidase, likely due to differences in crosslinking and formulation. Fillers with higher degradability, such as Restylane Kysse, may be preferable in high-risk areas or emergency reversal situations. These findings underscore the importance of filler selection in clinical practice and warrant further in vivo studies.