Stevens–Johnson syndrome: An adverse drug reaction with various drugs

This case series focuses on the different drugs that are responsible for the causation of SJS. This study was conducted at the ADR monitoring centre of the Pharmacovigilance Programme of India and Department of Psychiatry, Christian Medical College and Hospital, Ludhiana. A total of 10 patients were included in this study who suffered from SJS from various drugs. It is a descriptive study that was conducted for 1 year. This study includes 10 patients, all of them diagnosed with SJS. Out of these, 20% were children, 30% were adolescents, and 50% were adults. The group of drugs which were causing SJS included antibiotics (80%), anti-fungal (10%) and anti-epileptic drugs (10%). The individual drugs include 30% Cefixime, 20% Piperacillin Tazobactam, 10% Ceftriaxone, 10% Fluconazole, 10% Doxycycline, 10% Sulfadiazine, and 10% Oxcarbazepine. This case study has highlighted the drugs responsible for causing SJS, and more such cases can be reported through active surveillance.

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Publication Details

Journal
Indian Journal of Physiology and Pharmacology
Published
2025-08-22
DOI
https://doi.org/10.25259/ijpp_497_2023
Citations
3
Primary Topic
Drug-Induced Adverse Reactions
Type
article
Field-Weighted Citation Impact
4.18
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article

Stevens–Johnson syndrome: An adverse drug reaction with various drugs

Dinesh Badyal, Neena Bhatti, Girish Joseph, Prabhjot Kaur
3 citations
Indian Journal of Physiology and Pharmacology
Drug-Induced Adverse Reactions
4.18
article

Stevens–Johnson syndrome: An adverse drug reaction with various drugs

Dinesh Badyal, Neena Bhatti, Girish Joseph, Prabhjot Kaur
article en
3 citations

Abstract

This case series focuses on the different drugs that are responsible for the causation of SJS. This study was conducted at the ADR monitoring centre of the Pharmacovigilance Programme of India and Department of Psychiatry, Christian Medical College and Hospital, Ludhiana. A total of 10 patients were included in this study who suffered from SJS from various drugs. It is a descriptive study that was conducted for 1 year. This study includes 10 patients, all of them diagnosed with SJS. Out of these, 20% were children, 30% were adolescents, and 50% were adults. The group of drugs which were causing SJS included antibiotics (80%), anti-fungal (10%) and anti-epileptic drugs (10%). The individual drugs include 30% Cefixime, 20% Piperacillin Tazobactam, 10% Ceftriaxone, 10% Fluconazole, 10% Doxycycline, 10% Sulfadiazine, and 10% Oxcarbazepine. This case study has highlighted the drugs responsible for causing SJS, and more such cases can be reported through active surveillance.

Indian Journal of Physiology and PharmacologyVol. 69
Christian Medical College, Vellore (IN), Christian Medical College (IN)
Good health and well-being
Openalex Percentile: Top 6%
Drug-Induced Adverse Reactions
4.18
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