Figure 3 from Plasma Proteomic Analysis Reveals Complement System Changes in Irradiated Female BALB/c Mice during Mammary Carcinogenesis

<p>Network analysis of differentially expressed proteins in irradiated mice. <b>A–C,</b> Volcano plot of differentially expressed proteins in tumor-free mice from the IR group compared with controls at (<b>A</b>) 4 months, (<b>B</b>) 8 months, and (<b>C</b>) 18 months. <b>D,</b> Network analysis highlights the complement system as a predominant pathway. <b>E,</b> Pathway enrichment of complement systems indicated by gene ontology, components, and WIKI Pathways. Each colored circle in the table represents the placement of a protein within the network. Proteins that occur in multiple colors in the network indicate their simultaneous involvement in multiple highlighted pathways.</p>