The causal relationship between inflammatory cytokines and lung cancer: a two-sample bidirectional mendelian randomization study
This research indicates a possible causal link between inflammatory cytokines and lung cancer, highlighting the involvement of several inflammatory cytokines in the disease's development. It offers fresh perspectives on how inflammatory cytokines mediate the pathogenesis of lung cancer, holding great importance for prevention, treatment, and symptom enhancement of the disease.
Authors
- Wenhan Shi
- Rong Fan (ORCID: https://orcid.org/0000-0002-5922-483X)
- Ning Wang (ORCID: https://orcid.org/0000-0003-1745-1425)
- Shengxian Peng
- Kaiyang Zhao
- Ping-qing He
Institutions
- Nanchang University (CN)
- Henan University Huaihe Hospital and Huaihe Clinical Institute (CN)
- First Affiliated Hospital of Jiangxi Medical College (CN)
- Third Affiliated Hospital of Nanchang University (CN)
- Henan Provincial People's Hospital (CN)
- Zhengzhou People's Hospital (CN)
- Zigong First People's Hospital (CN)
- Henan Medical University (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-08-22
- DOI
- https://doi.org/10.1007/s12672-025-03256-x
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 0.00