Safety and Efficacy of Sequential Chemoimmunotherapy Followed by Concurrent Chemoradiation in Unresectable Stage III NSCLC

ID-chemo-ICI followed by cCRT seems feasible and safe for unresectable stage III NSCLC, particularly for patients unsuitable for upfront cCRT. Larger prospective trials are needed to validate these findings and optimize patient selection.

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Publication Details

Journal
JTO Clinical and Research Reports
Published
2025-08-22
DOI
https://doi.org/10.1016/j.jtocrr.2025.100890
Primary Topic
Lung Cancer Treatments and Mutations
Type
article
Field-Weighted Citation Impact
0.00

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article

Safety and Efficacy of Sequential Chemoimmunotherapy Followed by Concurrent Chemoradiation in Unresectable Stage III NSCLC

Sean S. Park, Dawn Owen, Konstantinos Leventakos, Arthi Sridhar et al.
JTO Clinical and Research Reports
Lung Cancer Treatments and Mutations
article

Safety and Efficacy of Sequential Chemoimmunotherapy Followed by Concurrent Chemoradiation in Unresectable Stage III NSCLC

Sean S. Park, Dawn Owen, Konstantinos Leventakos, Arthi Sridhar, Scott L. Hansen, Julian R. Molina, Katherine E. Smith, Aadel A. Chaudhuri, Aaron S. Mansfield, Mohamed Shanshal, Anastasios Dimou, Sydney Pulsipher, Kenneth W. Merrell, Yolanda I. Garces, Aditi P. Singh, Kaushal Parikh, Kenneth R. Olivier
article en

Abstract

ID-chemo-ICI followed by cCRT seems feasible and safe for unresectable stage III NSCLC, particularly for patients unsuitable for upfront cCRT. Larger prospective trials are needed to validate these findings and optimize patient selection.

JTO Clinical and Research ReportsVol. 6(11)
Mayo Clinic (US), WinnMed (US)
Mayo Foundation for Medical Education and Research
Openalex Percentile: Top 68%
Lung Cancer Treatments and Mutations
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