Application of low-coverage whole-genome sequencing technology in risk stratification of colorectal adenomas

The assessment of CIN correlates with both pathological subtypes and disease progression. UCAD-based detection of CIN contributes to the diagnosis of colorectal adenomas (CRA), with aberrations in chromosomes 7 and 8 potentially being closely associated with PLCRA.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-08-22
DOI
https://doi.org/10.3389/fonc.2025.1591548
Primary Topic
Genetic factors in colorectal cancer
Type
article
Field-Weighted Citation Impact
0.00

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article

Application of low-coverage whole-genome sequencing technology in risk stratification of colorectal adenomas

Jie Liu, Fang Yu, Qin Zhang, Zhili Guo et al.
Frontiers in Oncology
Genetic factors in colorectal cancer
article

Application of low-coverage whole-genome sequencing technology in risk stratification of colorectal adenomas

Jie Liu, Fang Yu, Qin Zhang, Zhili Guo, Xue Yuyue, Ren Dianqun
article en

Abstract

The assessment of CIN correlates with both pathological subtypes and disease progression. UCAD-based detection of CIN contributes to the diagnosis of colorectal adenomas (CRA), with aberrations in chromosomes 7 and 8 potentially being closely associated with PLCRA.

Frontiers in OncologyVol. 15
Jiaxing University (CN), Shanghai University of Traditional Chinese Medicine (CN), First Hospital of Jiaxing (CN)
Science and Technology Bureau of Jiaxing City
Openalex Percentile: Top 69%
Genetic factors in colorectal cancer
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