Untargeted metabolomics reveals the metabolic characteristics and biomarkers of obstetric antiphospholipid syndrome and undifferentiated connective tissue disease
This study systematically characterizes the metabolic reprogramming in OAPS, UCTD, and their comorbid states, identifying potential diagnostic biomarkers. Differential metabolites and pathway analyses highlight the critical role of immunity, contributing to a theoretical framework for "metabolism-immunity-vascular" interactions.
Authors
- Siyin Li
- Xuemin Jian
- Jing Yang (ORCID: https://orcid.org/0000-0002-7439-4802)
- Juan Shi (ORCID: https://orcid.org/0000-0003-3025-6456)
- Jinmei Zou
- Xiaolei Shu
Institutions
- Mianyang Central Hospital (CN)
Publication Details
- Journal
- Frontiers in Molecular Biosciences
- Published
- 2025-08-22
- DOI
- https://doi.org/10.3389/fmolb.2025.1632244
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00