Chemotherapy-induced alterations in miRNA expression and their prognostic implications in ovarian cancer
The study highlights differential regulation of circulating and tissue miRNAs in Indian OC patients, emphasizing the selective retention of oncogenic miRNAs in tumors and release of tumor suppressive miRNAs into circulation. These findings support the utility of miRNAs as diagnostic and prognostic biomarkers in OC.
Authors
- Jayanti Mania‐Pramanik (ORCID: https://orcid.org/0000-0002-5310-2479)
- Samruddhi Ranmale (ORCID: https://orcid.org/0000-0002-7800-6985)
- Sanket Mehta (ORCID: https://orcid.org/0000-0001-8077-7861)
- Vashishth Maniar
- Pavan Kumar (ORCID: https://orcid.org/0000-0001-6845-9959)
- Hemant Tongaonkar
Institutions
- National Institute for Research in Reproductive Health (IN)
- P. D. Hinduja Hospital and Medical Research Centre (IN)
- Saifee Hospital (IN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-08-22
- DOI
- https://doi.org/10.3389/fonc.2025.1580565
- Citations
- 1
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- Indian Council of Medical Research