Storage damage of cold-stored whole blood in CPDA maintenance fluid during the whole effective storage period
These findings show that CS-WB maintained within 14 days of storage provides optimal preservation of critical hemostatic properties, including RBCs oxygen-carrying capacity, coagulation factors function, and platelets hemostatic performance. This storage window holds particular clinical relevance for hemorrhagic shock resuscitation in resource-constrained scenarios, such as military medicine or prehospital trauma care systems.
Authors
- Zihan Yuan
- Yingyu He
- W Liu
- Lidong Zhang (ORCID: https://orcid.org/0000-0002-0501-6162)
- Yingkai Xu
- Lei Liu
- Junying Li (ORCID: https://orcid.org/0000-0002-5782-2051)
- Yiquan Zhang (ORCID: https://orcid.org/0000-0003-3935-4079)
- Feng Cheng (ORCID: https://orcid.org/0000-0002-5599-460X)
Institutions
- Nantong University (CN)
- Wuhan Puai Hospital (CN)
- Central Hospital of Wuhan (CN)
- Wuhan General Hospital of Guangzhou (CN)
- Wuhan University of Science and Technology (CN)
Publication Details
- Journal
- Frontiers in Cell and Developmental Biology
- Published
- 2025-08-22
- DOI
- https://doi.org/10.3389/fcell.2025.1610009
- Primary Topic
- Blood transfusion and management
- Type
- article
- Field-Weighted Citation Impact
- 0.00