Distinct effects of adjuvants on B cell responses to protein or polysaccharide antigens contained in glycoconjugate vaccines
Investigating the antibody quantity and quality and local and systemic B-cell population expansions in a naive model supports our understanding of how different adjuvants shape the response to the tested polysaccharidic antigens.
Authors
- Chiara Sammicheli
- Sonia Budroni (ORCID: https://orcid.org/0000-0002-6142-5155)
- Erica Borgogni
- Monia Bardelli (ORCID: https://orcid.org/0000-0002-9722-024X)
- Oretta Finco (ORCID: https://orcid.org/0000-0002-8652-6534)
- Francesca Buricchi (ORCID: https://orcid.org/0000-0003-3306-3588)
- Elisa Faenzi
- Fabiana Spensieri (ORCID: https://orcid.org/0000-0003-4922-2395)
- Maria Rosaria Romano (ORCID: https://orcid.org/0009-0006-8568-2363)
- Evita Balducci
- Bruno Galletti (ORCID: https://orcid.org/0000-0003-0673-5406)
- Ugo D’Oro (ORCID: https://orcid.org/0000-0002-7657-8605)
- Gianfranco Volpini
- Simona Tavarini
Institutions
- Toscana Life Sciences (IT)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-08-22
- DOI
- https://doi.org/10.3389/fimmu.2025.1574941
- Primary Topic
- Immunotherapy and Immune Responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- GlaxoSmithKline