Reduced circulating regulatory T cells in primary Sjögren’s syndrome: the contribution of enhanced apoptosis and impaired survival
These data suggest that the decreased peripheral abundance and increased apoptosis of Treg cells play an important role in the pathogenesis of pSS. Therefore, approaches for increasing Treg numbers <i>in vivo</i> could provide precise pSS therapy.
Authors
- Yuhan Jia (ORCID: https://orcid.org/0000-0003-3516-6337)
- Chong Gao (ORCID: https://orcid.org/0000-0001-7639-0808)
- Jing Luo (ORCID: https://orcid.org/0000-0002-1242-0286)
- Hui Guo (ORCID: https://orcid.org/0000-0001-6769-1772)
- Min Feng (ORCID: https://orcid.org/0000-0002-4068-8511)
- Yan Qin (ORCID: https://orcid.org/0000-0003-4729-6673)
- Yanlin Wang (ORCID: https://orcid.org/0000-0003-0995-2393)
- Xiangcong Zhao
- Zhaojun Liang
Institutions
- Brigham and Women's Hospital (US)
- Shanxi Medical University (CN)
- Second Hospital of Shanxi Medical University (CN)
- Shenzhen Bao'an District People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-08-22
- DOI
- https://doi.org/10.3389/fimmu.2025.1603305
- Primary Topic
- Salivary Gland Disorders and Functions
- Type
- article
- Field-Weighted Citation Impact
- 0.00