Effects of amiodarone infusion on clinical parameters in the cardiac intensive care unit: what does it do to heart rate and oxygen delivery?

Amiodarone infusions are associated with a significant decrease in heart rate without greatly impacting oxygen delivery or requiring increased vasoactive support. Heart rate decreases most until a cumulative dose of 30,000 mcg/kg, and heart rate decrease is most pronounced in those with ventricular tachycardia.