Pustular reaction in adult-onset immunodeficiency due to anti-interferon-gamma autoantibodies
Among patients presenting with sterile pustular eruptions, the presence of lymphadenopathy, hepatomegaly, and splenomegaly served as perfect clinical predictors of an underlying pustular reaction associated with AOID. In cases where these hallmark features were absent, a predictive algorithm incorporating the presence of a concomitant infections, serum globulin concentration, and alkaline phosphatase level demonstrated robust utility in estimating the likelihood of AOID-associated pustular reaction.
Authors
- Napatra Tovanabutra (ORCID: https://orcid.org/0000-0002-9463-5976)
- Salin Kiratikanon (ORCID: https://orcid.org/0000-0002-1597-7290)
- Narachai Julanon (ORCID: https://orcid.org/0000-0002-4374-1170)
- Romanee Chaiwarith (ORCID: https://orcid.org/0000-0002-1241-5954)
- Phichayut Phinyo (ORCID: https://orcid.org/0000-0002-8543-6254)
- Ploenchan Chetchotisakd (ORCID: https://orcid.org/0000-0001-9501-5827)
- Suteeraporn Chaowattanapanit (ORCID: https://orcid.org/0000-0002-8954-7672)
- Pojsakorn Danpanichkul (ORCID: https://orcid.org/0000-0002-9121-165X)
- Siriluck Anunnatsiri (ORCID: https://orcid.org/0000-0002-6772-4957)
- Charoen Choonhakarn (ORCID: https://orcid.org/0000-0002-3417-6210)
- Mati Chuamanochan (ORCID: https://orcid.org/0000-0002-6654-3409)
- Siri Chiewchanvit (ORCID: https://orcid.org/0000-0001-9634-9650)
- Rujira Rujiwetpongstorn (ORCID: https://orcid.org/0000-0002-0256-9343)
Institutions
- Texas Tech University (US)
- Khon Kaen University (TH)
- Chiang Mai University (TH)
- Texas Tech University Health Sciences Center (US)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-08-22
- DOI
- https://doi.org/10.3389/fimmu.2025.1619832
- Primary Topic
- Immunodeficiency and Autoimmune Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00