The cyclic nucleotide-gated channels CNGC2 and CNGC4 support systemic wound responses in Arabidopsis thaliana

CNGC2 and CNGC4 likely play roles in spreading the Ca2+ signal through systemic leaves to help further propagate and amplify the plant-wide wound response. Although CNGC19 has previously been shown to be involved in Ca2+ signaling at the wound site, knockouts in this gene did not disrupt the long-distance element of the wound response. These findings suggest that the molecular machinery required to trigger the local reaction to damage is likely, at least in part, distinct from the activities that support the systemic spread of the response throughout the plant.