Carotid calcium burden and perivascular fat density on computed tomography angiography as predictors of outcomes after carotid endarterectomy
High ipsilateral carotid artery calcium score independently predicted the risk of MACE and cardiovascular mortality after CEA and was associated with a trend toward increased all-cause mortality up to 4 years of follow-up. Predictive values were even stronger in asymptomatic patients. Perivascular fat density seems to be relevant to predict restenosis. These plaque characteristics may help identify patients most likely to benefit from CEA and those who may require intensified postoperative cardiovascular risk management due to elevated complication risk.
Authors
- Reinoud P.H. Bokkers (ORCID: https://orcid.org/0000-0001-6130-7311)
- Clark J. Zeebregts (ORCID: https://orcid.org/0000-0002-5011-4124)
- Maarten Uyttenboogaart (ORCID: https://orcid.org/0000-0002-6934-4456)
- Jean‐Paul P.M. de Vries (ORCID: https://orcid.org/0000-0002-2669-320X)
- Richte C. L. Schuurmann (ORCID: https://orcid.org/0000-0001-7253-3939)
- Robert A. Pol (ORCID: https://orcid.org/0000-0002-2236-5233)
- Sandro Lepidi (ORCID: https://orcid.org/0000-0003-2201-6081)
- Franziska Röder
- Maud M. Koek
- Mario D’Oria (ORCID: https://orcid.org/0000-0002-7156-7827)
- Riccardo Rebuzzi
Institutions
- University Medical Center Groningen (NL)
- University of Trieste (IT)
- University of Groningen (NL)
Publication Details
- Journal
- Journal of Vascular Surgery
- Published
- 2025-08-22
- DOI
- https://doi.org/10.1016/j.jvs.2025.08.023
- Primary Topic
- Cerebrovascular and Carotid Artery Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00