Assocation Between a Brain Care Score Derived from Participant Responses and Incident Stroke from the COSMOS Study
A BCS derived from participant responses showed similar predictive performance and discriminatory ability compared to previous validation studies that use physical and laboratory measurements. Future studies could consider incorporating the BCS derived from participant responses when physical and laboratory measurements are not readily available.
Authors
- Pamela M. Rist (ORCID: https://orcid.org/0000-0003-3543-045X)
- Christopher D. Anderson (ORCID: https://orcid.org/0000-0002-0053-2002)
- Howard D. Sesso (ORCID: https://orcid.org/0000-0002-9698-9954)
- Aladdin H. Shadyab (ORCID: https://orcid.org/0000-0002-9693-0522)
- Nirupama Yechoor
- Sanjula Singh (ORCID: https://orcid.org/0000-0001-9304-8107)
- Savvina Prapiadou (ORCID: https://orcid.org/0000-0001-7415-2566)
- Jasper R. Senff (ORCID: https://orcid.org/0009-0002-6540-480X)
- Benjamin Yong‐Qiang Tan (ORCID: https://orcid.org/0000-0003-1824-9077)
- JoAnn E. Manson (ORCID: https://orcid.org/0000-0002-9426-7595)
- Taylor McVeigh
- Tamara N. Kimball (ORCID: https://orcid.org/0000-0002-1107-0771)
- H. Bart Brouwers (ORCID: https://orcid.org/0000-0001-7044-8394)
- Reinier W. P. Tack (ORCID: https://orcid.org/0000-0003-3204-0309)
- Jonathan Rosand
- Devanshi Choksi (ORCID: https://orcid.org/0009-0009-6312-5621)
- Tanzeela Ranman
Institutions
- Broad Institute (US)
- Twitter (United States) (US)
- Brigham and Women's Hospital (US)
- Harvard University (US)
- University Medical Center Utrecht (NL)
- Massachusetts General Hospital (US)
- Human Longevity (United States) (US)
- National University Health System (SG)
- Mass General Brigham (US)
Publication Details
- Journal
- American Journal of Lifestyle Medicine
- Published
- 2025-08-22
- DOI
- https://doi.org/10.1177/15598276251368345
- Primary Topic
- Health, Environment, Cognitive Aging
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Pfizer
- National Heart and Lung Institute
- NIH Clinical Center