Glycaemic responses to metformin monotherapy by <scp>SNP</scp> clusters in patients with type 2 diabetes
These findings suggest that PRS derived from beta-cell dysfunction clusters may help predict glycaemic response to metformin and support the potential for genetically guided treatment in T2D.
Authors
- Wayne Huey‐Herng Sheu (ORCID: https://orcid.org/0000-0002-8805-8340)
- Konstantinos Hatzikotoulas (ORCID: https://orcid.org/0000-0002-4699-3672)
- Ken Suzuki (ORCID: https://orcid.org/0000-0003-1065-3593)
- Chun‐Yi Lee (ORCID: https://orcid.org/0000-0002-4210-206X)
- Andrew P. Morris
- Tzu‐Hung Hsiao (ORCID: https://orcid.org/0000-0003-0365-9970)
- Jerome I. Rotter
- Yii‐Der Ida Chen
- Cai‐Sian Liao
- Yi‐Wen Wang
Institutions
- Fu Jen Catholic University (TW)
- National Chung Hsing University (TW)
- National Health Research Institutes (TW)
- UCLA Medical Center (US)
- Taipei Veterans General Hospital (TW)
- University of Manchester (GB)
- Helmholtz Zentrum München (DE)
- Taichung Veterans General Hospital (TW)
- Arthritis UK (GB)
- Taipei Hospital (TW)
- Institute of Statistical Science, Academia Sinica (TW)
- Harbor–UCLA Medical Center (US)
- National Defense Medical Center (TW)
- The University of Tokyo (JP)
Publication Details
- Journal
- Diabetes Obesity and Metabolism
- Published
- 2025-08-22
- DOI
- https://doi.org/10.1111/dom.70023
- Primary Topic
- Metabolism, Diabetes, and Cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Academia Sinica
- National Health Research Institutes
- National Science and Technology Council