Predictive immunonutritional biomarkers for the severity and recovery of sudden sensorineural hearing loss: a prospective clinical study
In patients with SSNHL, PNI levels were significantly lowered, while SII levels were significantly higher. Furthermore, a negative correlation was observed between these two indicators. A negative correlation between PNI and SSNHL severity and a positive correlation between SII and severity were observed. These findings suggest that PNI and SII could serve as potential biomarkers for predicting SSNHL prognosis.
Authors
- Chunping Yang (ORCID: https://orcid.org/0000-0003-3987-2722)
- Weili Guo (ORCID: https://orcid.org/0000-0003-4459-9978)
- Xu Zhang (ORCID: https://orcid.org/0009-0009-3257-1012)
- Bing Guan (ORCID: https://orcid.org/0000-0002-9988-0743)
Institutions
- Nanchang University (CN)
- Xuzhou Medical College (CN)
- First Affiliated Hospital of Jiangxi Medical College (CN)
- Huaian First People’s Hospital (CN)
- Second Affiliated Hospital of Nanchang University (CN)
- Second People’s Hospital of Huai’an (CN)
- Northern Jiangsu People's Hospital (CN)
- Xuzhou No.1 People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2025-08-22
- DOI
- https://doi.org/10.3389/fneur.2025.1542386
- Primary Topic
- Vestibular and auditory disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China