Figure 5 from Plasma Proteomic Analysis Reveals Complement System Changes in Irradiated Female BALB/c Mice during Mammary Carcinogenesis

<p>Complement system proteins of plasma from TB mice compared with similarly aged non-TB mice. <b>A,</b> Heatmap representing unsupervised clustering of complement system components in TB mice (red bottom bar) vs. tumor-free mice at termination (blue bottom bar). Unsupervised clustering using Euclidian distance and Ward.D.2. <b>B,</b> Differential expression of complement C1q family members, a, b, and c, in TB treated as indicated. Bars represent means (<i>n</i> = 4) and SE. Statistical significance between treatment groups for each complement component defined by a two-way ANOVA is denoted by asterisks above the bars. *, <i>P</i> < 0.05; **, <i>P</i> < 0.01.</p>