Association between atherogenic index of plasma and risk of type 2 diabetes mellitus and the mediating effect of BMI: a comparative analysis in Chinese and Japanese populations
Our findings reveal substantial population-specific differences in the AIP-T2DM relationship, including population-specific thresholds and mediation pathways. These results underscore the importance of population-tailored screening strategies and suggest that interventions targeting lipid metabolism and BMI management may have varying efficacy across East Asian populations.
Authors
- Changchun Cao (ORCID: https://orcid.org/0000-0003-1992-4257)
- Haofei Hu (ORCID: https://orcid.org/0000-0001-6061-6796)
- Yong Han (ORCID: https://orcid.org/0000-0001-6149-3724)
- Yuheng Liao
- Haiying Song (ORCID: https://orcid.org/0000-0003-4086-6194)
Institutions
- Shenzhen University (CN)
- First Affiliated Hospital of Guangdong Pharmaceutical University (CN)
- Shenzhen Second People's Hospital (CN)
Publication Details
- Journal
- Diabetology & Metabolic Syndrome
- Published
- 2025-08-22
- DOI
- https://doi.org/10.1186/s13098-025-01907-1
- Citations
- 4
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 5.42
Funders
- Shenzhen University
- Sanming Project of Medicine in Shenzhen