Association of first-trimester exposure to Kampo medicines containing Prunus persica kernel with preterm birth and major congenital malformations: a Japanese database study
There was no significant difference in the risk of preterm birth or MCMs between pregnant women prescribed KPK and those prescribed TSS during the first trimester.
Authors
- Taku Obara (ORCID: https://orcid.org/0000-0002-3674-1674)
- Ryutaro Arita (ORCID: https://orcid.org/0000-0003-4676-7242)
- Minoru Ohsawa (ORCID: https://orcid.org/0000-0002-5417-8248)
- Tomofumi Ishikawa (ORCID: https://orcid.org/0000-0002-0901-368X)
- Shin Takayama (ORCID: https://orcid.org/0000-0002-6388-4566)
- Akiko Kikuchi (ORCID: https://orcid.org/0000-0001-8368-0651)
- Ken Haneda
- Nariyasu Mano (ORCID: https://orcid.org/0000-0003-1679-9024)
- Takamasa Sakai (ORCID: https://orcid.org/0000-0001-9086-6999)
- Aoi Noda (ORCID: https://orcid.org/0000-0002-7644-6848)
- Mami Ishikuro (ORCID: https://orcid.org/0000-0002-2884-0023)
- Masatsugu Orui (ORCID: https://orcid.org/0000-0002-4871-8455)
- Shinichi Kuriyama (ORCID: https://orcid.org/0000-0003-2526-2974)
- Genki Shinoda
- Tadashi Ishii
- Satoko Suzuki
- Tadaharu Kunitoki
Institutions
- Tohoku University (JP)
- Tohoku University Hospital (JP)
- Tohoku Medical Megabank Organization (JP)
- Meijo University (JP)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-08-22
- DOI
- https://doi.org/10.3389/fphar.2025.1562724
- Citations
- 1
- Primary Topic
- Phytoestrogen effects and research
- Type
- article
- Field-Weighted Citation Impact
- 1.47
Funders
- Japan Society for the Promotion of Science