An Intriguing Case Report of Type 2 AutoimmunePolyendocrine Syndrome Post-SARS-CoV-2: Causeor Coincidence?
This case adds to limited evidence suggesting a possible link between SARS-CoV-2 infection and the onset or unmasking of APS-2. While a direct causal role of the virus remains uncertain, SARS-CoV-2 may function as an environmental trigger, accelerating the transition from subclinical to clinical autoimmunity in genetically susceptible patients. This observation supports the need for clinical vigilance in post-COVID-19 patients presenting with nonspecific but suggestive endocrine symptoms.
Authors
- Caterina Mian (ORCID: https://orcid.org/0000-0003-2615-8001)
- C. Betterle
- Marianna Torchio
- Giacomo Voltan (ORCID: https://orcid.org/0000-0002-3628-0492)
- Chiara Sabbadin (ORCID: https://orcid.org/0000-0003-1526-6832)
- Andrea Graziani (ORCID: https://orcid.org/0000-0002-3239-2374)
Institutions
- University of Padua (IT)
Publication Details
- Journal
- Endocrine Metabolic & Immune Disorders - Drug Targets
- Published
- 2025-08-18
- DOI
- https://doi.org/10.2174/0118715303407830250807114958
- Primary Topic
- Adrenal Hormones and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00