Association of 14-3-3η with Tumor Necrosis Factor (TNF-α) and Matrix Metalloproteinase-1 (MMP-1) in Rheumatoid Arthritis
Serum 14-3-3η may serve as a supportive biomarker for the diagnosis of early rheumatoid arthritis and assessment of disease activity. Its correlation with TNF-α reflects a potential link to inflammatory burden. Further large-scale, longitudinal studies are needed to confirm its clinical utility.
Authors
- Murk Fatima (ORCID: https://orcid.org/0000-0002-2108-4894)
- Samra Bokhari
- Sofia Amjad (ORCID: https://orcid.org/0000-0003-1570-1304)
- Mehreen Inam Illahi (ORCID: https://orcid.org/0000-0003-4174-0999)
- Huma Salahuddin
Institutions
- Superior University (PK)
- National Institute of Child Health (PK)
- Ziauddin University (PK)
Publication Details
- Journal
- Current Rheumatology Reviews
- Published
- 2025-08-22
- DOI
- https://doi.org/10.2174/0115733971375944250811060418
- Primary Topic
- 14-3-3 protein interactions
- Type
- article
- Field-Weighted Citation Impact
- 0.00