Association of 14-3-3η with Tumor Necrosis Factor (TNF-α) and Matrix Metalloproteinase-1 (MMP-1) in Rheumatoid Arthritis

Serum 14-3-3η may serve as a supportive biomarker for the diagnosis of early rheumatoid arthritis and assessment of disease activity. Its correlation with TNF-α reflects a potential link to inflammatory burden. Further large-scale, longitudinal studies are needed to confirm its clinical utility.

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Publication Details

Journal
Current Rheumatology Reviews
Published
2025-08-22
DOI
https://doi.org/10.2174/0115733971375944250811060418
Primary Topic
14-3-3 protein interactions
Type
article
Field-Weighted Citation Impact
0.00
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article

Association of 14-3-3η with Tumor Necrosis Factor (TNF-α) and Matrix Metalloproteinase-1 (MMP-1) in Rheumatoid Arthritis

Murk Fatima, Samra Bokhari, Sofia Amjad, Mehreen Inam Illahi et al.
Current Rheumatology Reviews
14-3-3 protein interactions
article

Association of 14-3-3η with Tumor Necrosis Factor (TNF-α) and Matrix Metalloproteinase-1 (MMP-1) in Rheumatoid Arthritis

Murk Fatima, Samra Bokhari, Sofia Amjad, Mehreen Inam Illahi, Huma Salahuddin
article en

Abstract

Serum 14-3-3η may serve as a supportive biomarker for the diagnosis of early rheumatoid arthritis and assessment of disease activity. Its correlation with TNF-α reflects a potential link to inflammatory burden. Further large-scale, longitudinal studies are needed to confirm its clinical utility.

Current Rheumatology ReviewsVol. 22(1)
Superior University (PK), National Institute of Child Health (PK), Ziauddin University (PK)
Openalex Percentile: Top 81%
14-3-3 protein interactions
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