Inclusion Complexes of α and β -cyclodextrin with Canagliflozin Hemihydrate: Design and Characterization
Inclusion complexation with α-CD and β-CD significantly improved the solubility and dissolution of CANA in aqueous medium. These findings suggest that cyclodextrin-based inclusion complexes offer a promising approach to enhancing the biopharmaceutical performance of poorly soluble drugs, such as CANA.
Authors
- Ajay Semalty (ORCID: https://orcid.org/0000-0002-2512-8516)
- Mukul Gupta (ORCID: https://orcid.org/0000-0002-9622-656X)
- Mona Semalty (ORCID: https://orcid.org/0000-0001-7611-6366)
- Archna Sagdeo (ORCID: https://orcid.org/0000-0001-9961-1650)
- Radheshyam Radheshyam
- Priyanka Gauniya (ORCID: https://orcid.org/0000-0003-3374-9141)
- Chitra Chitra
- Mukesh Pandey (ORCID: https://orcid.org/0009-0002-8204-4631)
Institutions
- Raja Ramanna Centre for Advanced Technology (IN)
- Hemwati Nandan Bahuguna Garhwal University (IN)
- Homi Bhabha National Institute (IN)
- Himalayan University (IN)
- UGC DAE Consortium for Scientific Research (IN)
Publication Details
- Journal
- Current Pharmaceutical Design
- Published
- 2025-08-22
- DOI
- https://doi.org/10.2174/0113816128384484250729091344
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00