Analysis of novel therapeutic targets and construction of a prognostic model for hepatocellular carcinoma
This study, for the first time, integrated multi-omics data and experimental verification to establish a prognostic model of HCC based on the ferroptosis gene. It can be used to dynamically monitor HCC using blood tests and provide a new target for personalized immunotherapy.
Authors
- Hua Guan (ORCID: https://orcid.org/0000-0001-6329-6273)
- Dafei Xie (ORCID: https://orcid.org/0000-0002-4854-8986)
- Wenfeng Li (ORCID: https://orcid.org/0000-0001-7213-8648)
- Xin Huang (ORCID: https://orcid.org/0000-0002-6569-0095)
- Pengyuan Lei (ORCID: https://orcid.org/0009-0004-7145-3741)
- Bo Huang (ORCID: https://orcid.org/0000-0002-1776-6411)
Institutions
- Beijing Radiation Center (CN)
- University of South China (CN)
Publication Details
- Journal
- PeerJ
- Published
- 2025-08-22
- DOI
- https://doi.org/10.7717/peerj.19899
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Hunan Province