Kappa free light chain concentration in serum is reduced after CD20-depletion with ocrelizumab
Treatment with ocrelizumab reduces serum KFLC concentration in MS patients. However, serum KFLC concentration is not able to predict disease activity in these MS patients.
Authors
- Thomas Skripuletz (ORCID: https://orcid.org/0000-0001-8550-335X)
- Stefan Gingele (ORCID: https://orcid.org/0000-0002-6055-5695)
- Nora Möhn
- Sandra Nay (ORCID: https://orcid.org/0000-0002-4986-1181)
- Gudrun Körner (ORCID: https://orcid.org/0000-0003-1919-0070)
- Refik Pul (ORCID: https://orcid.org/0000-0002-8940-9317)
- Philipp Schwenkenbecher (ORCID: https://orcid.org/0000-0002-1260-1650)
- Kurt‐Wolfram Sühs (ORCID: https://orcid.org/0000-0002-8077-481X)
- Elke Voß
- Franz Felix Konen (ORCID: https://orcid.org/0000-0002-8609-5674)
- Lea Grote‐Levi
- Konstantin Fritz Jendretzky
- Martin W. Hümmert (ORCID: https://orcid.org/0000-0002-5928-2343)
- Torsten Witte
- Philipp Sebastian Gehring
Institutions
- University of Zurich (CH)
- Medizinische Hochschule Hannover (DE)
- University Hospital of Zurich (CH)
- Essen University Hospital (DE)
- See-Spital (CH)
- Stadtspital Waid (CH)
Publication Details
- Journal
- Neurological Research and Practice
- Published
- 2025-08-22
- DOI
- https://doi.org/10.1186/s42466-025-00419-7
- Citations
- 1
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.47