Association of TNF and TLR2 genes with blood parameter levels in Mexican patients with schizophrenia

Our findings indicate that blood parameter levels may be affected by genetic variants of TNF and TLR2 genes, indicating a potential role for innate immune response activation in schizophrenia in the Mexican population. Further studies with larger cohorts and comprehensive genetic analyses are essential to validate these findings and clarify the role of innate immune genes in schizophrenia.

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Publication Details

Journal
BMC Psychiatry
Published
2025-08-22
DOI
https://doi.org/10.1186/s12888-025-07270-9
Primary Topic
Tryptophan and brain disorders
Type
article
Field-Weighted Citation Impact
0.00

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article

Association of TNF and TLR2 genes with blood parameter levels in Mexican patients with schizophrenia

Joanna Jiménez‐Pavón, Beatríz Camarena, Héctor Cabello-Rangel, Marco Antonio Sanabrais‐Jiménez et al.
BMC Psychiatry
Tryptophan and brain disorders
article

Association of TNF and TLR2 genes with blood parameter levels in Mexican patients with schizophrenia

Joanna Jiménez‐Pavón, Beatríz Camarena, Héctor Cabello-Rangel, Marco Antonio Sanabrais‐Jiménez, Carlo Esteban Sotelo-Ramírez, Ingrid Pamela Morales-Cedillo
article en

Abstract

Our findings indicate that blood parameter levels may be affected by genetic variants of TNF and TLR2 genes, indicating a potential role for innate immune response activation in schizophrenia in the Mexican population. Further studies with larger cohorts and comprehensive genetic analyses are essential to validate these findings and clarify the role of innate immune genes in schizophrenia.

BMC PsychiatryVol. 25(1)
Hospital Juárez de México (MX), Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz (MX)
Instituto Nacional de Psiquiatría Ramón de la Fuente Muñiz
Good health and well-being
Openalex Percentile: Top 79%
Tryptophan and brain disorders
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