Integrating Machine Learning and Multiomics Analyses to Identify Immune-Related Biomarkers and Mechanisms in Primary Biliary Cholangitis
By integrating machine learning and functional analyses, this study identified 4 genes that may serve as potential biomarkers for PBC. Their involvement in immune regulation suggests possible applications in both diagnosis and therapy. Further studies are necessary to explore their clinical relevance and therapeutic potential.
Authors
- Longke Xie
- Ying Liang (ORCID: https://orcid.org/0000-0002-4939-8705)
- Zhiyu Zeng (ORCID: https://orcid.org/0000-0002-7383-2700)
- L L Chen (ORCID: https://orcid.org/0009-0005-6304-9738)
- Dongliang Li (ORCID: https://orcid.org/0000-0001-5536-8468)
- Lei Xia (ORCID: https://orcid.org/0000-0001-9749-3435)
- Jian Fang (ORCID: https://orcid.org/0000-0001-7598-1091)
Institutions
- Fujian University of Traditional Chinese Medicine (CN)
- Fujian Medical University (CN)
- 117th Hospital of People's Liberation Army (CN)
Publication Details
- Journal
- Clinical and Translational Gastroenterology
- Published
- 2025-08-22
- DOI
- https://doi.org/10.14309/ctg.0000000000000907
- Primary Topic
- Liver Diseases and Immunity
- Type
- article
- Field-Weighted Citation Impact
- 0.00