Cell-targeted PD-1 agonists are potent NK-cell inhibitors
Targeted PD-1 agonist molecules, inhibiting T cells and NK cells in a tissue-specific manner offer a new promising treatment for autoimmune and inflammatory diseases.
Authors
- Hussein Al‐Mossawi (ORCID: https://orcid.org/0000-0002-2312-3754)
- Guillaume Rieunier (ORCID: https://orcid.org/0000-0002-0380-3648)
- David X. Overton
- Eduardo Mateos-Díaz (ORCID: https://orcid.org/0000-0003-2816-9775)
- Giovanna Bossi
- Charlotte Viant (ORCID: https://orcid.org/0000-0002-8852-2318)
- Alice Newey (ORCID: https://orcid.org/0000-0002-1628-6758)
- Hilda Pope
- Tara Mahon
- Ana L. Chiodetti
Institutions
- Immunocore (United Kingdom) (GB)
- University of Bath (GB)
- Bath Spa University (GB)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-08-22
- DOI
- https://doi.org/10.3389/fimmu.2025.1640509
- Citations
- 1
- Primary Topic
- Immune Cell Function and Interaction
- Type
- article
- Field-Weighted Citation Impact
- 0.80