Effect of rubusoside, a natural sucrose substitute, on the metabolism of Scardovia wiggsiae: a novel potential cariogenic pathogen
Rubusoside exhibits a significant bacteriostatic effect against S. wiggsiae, a potential pathogen associated with early childhood dental caries. Notably, its inhibitory activity remains unaffected even in the presence of sucrose. Consequently, as a sucrose substitute or sweetener additive, rubusoside holds broad application prospects in both the food industry and oral hygiene products, offering a promising approach to the prevention and treatment of dental caries.
Authors
- Rong Ma (ORCID: https://orcid.org/0000-0002-9865-3047)
- Yisha Lin
- Dandan Ma (ORCID: https://orcid.org/0000-0003-4484-9455)
- Yuanyuan Zhang (ORCID: https://orcid.org/0000-0002-3765-7298)
- Yimin Wang (ORCID: https://orcid.org/0000-0003-0191-240X)
- Peiling Wang (ORCID: https://orcid.org/0000-0003-4202-7570)
- Jinpu Chu
Institutions
- Zhengzhou University (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- BMC Biology
- Published
- 2025-08-22
- DOI
- https://doi.org/10.1186/s12915-025-02321-9
- Citations
- 2
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 2.93
Funders
- Natural Science Foundation of Henan Province