An integrative bioinformatics approach unveils fibrosis-driven prognostic signature and immunotherapeutic potential in kidney renal clear cell carcinoma
The fibrosis-related signature effectively stratifies KIRC patients according to prognosis and potential immunotherapy responses, enhancing our understanding of fibrosis-mediated tumor biology and enabling personalized therapeutic approaches in kidney cancer.
Authors
- Jun-Mei Lai (ORCID: https://orcid.org/0009-0005-6566-0098)
- Chen Zhang (ORCID: https://orcid.org/0000-0002-3579-6980)
- Wenjing Wu (ORCID: https://orcid.org/0009-0005-2130-6580)
Institutions
- Jinhua Academy of Agricultural Sciences (CN)
- Guang Fu Hospital (CN)
- Zhejiang Provincial People's Hospital (CN)
- Jinhua Central Hospital (CN)
- Hangzhou Medical College (CN)
Publication Details
- Journal
- Toxicology and Applied Pharmacology
- Published
- 2025-08-22
- DOI
- https://doi.org/10.1016/j.taap.2025.117533
- Primary Topic
- Renal cell carcinoma treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00