Genetic regulation of sperm DNA methylation in cattle through meQTL mapping
For the first time, meQTLs have been detected and characterized in bovine sperm, contributing to a better understanding of the transmission of paternally inherited DNAm marks. These findings provide useful information for further research aimed at integrating epigenetic information into the prediction of performance traits.
Authors
- Mekki Boussaha (ORCID: https://orcid.org/0000-0002-5432-4604)
- Ananth N. Shankar
- Hélène Kiefer (ORCID: https://orcid.org/0000-0002-6631-741X)
- Valentin Costes (ORCID: https://orcid.org/0000-0002-8959-1489)
- F. Besnard (ORCID: https://orcid.org/0000-0002-1187-9132)
- Gabriel Costa Monteiro Moreira (ORCID: https://orcid.org/0000-0003-3139-1027)
- Eli Sellem (ORCID: https://orcid.org/0000-0001-9251-9077)
- Marie-Christine Deloche (ORCID: https://orcid.org/0009-0001-9181-8929)
- Didier Boichard (ORCID: https://orcid.org/0000-0003-0361-2961)
- Chrystelle Le Danvic (ORCID: https://orcid.org/0000-0003-3969-1542)
- Marie-Pierre Sanchez (ORCID: https://orcid.org/0000-0002-1371-5342)
- Aurélie Allais‐Bonnet (ORCID: https://orcid.org/0000-0002-5484-0270)
- Chris Hozé (ORCID: https://orcid.org/0000-0002-5900-5506)
- Sébastien Fritz (ORCID: https://orcid.org/0000-0002-3378-1048)
- Corentin Fouéré (ORCID: https://orcid.org/0009-0005-8735-2918)
- Aurélie Chaulot‐Talmon
- Francesca Ali
- Hélène Jammes
- Valentin Sorin
Institutions
- École Nationale Vétérinaire d'Alfort (FR)
- ParisTech (FR)
- Université de Versailles Saint-Quentin-en-Yvelines (FR)
- AgroParisTech (FR)
- Université Paris-Saclay (FR)
- Microbiologie de l’alimentation au service de la santé (FR)
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR)
- Elice (France) (FR)
- Biologie de la Reproduction, Environnement, Epigénétique et Développement (FR)
Publication Details
- Journal
- BMC Genomics
- Published
- 2025-08-22
- DOI
- https://doi.org/10.1186/s12864-025-11934-x
- Citations
- 2
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- APIS-GENE
- Agence Nationale de la Recherche
- Association Nationale de la Recherche et de la Technologie