Streptococcus agalactiae Meningoencephalitis Revealing Spondylodiscitis in a Diabetic Patient

<i>Streptococcus agalactiae</i> is a well-known pathogen responsible for neonatal and postpartum infections. An increase in the incidence of invasive <i>Streptococcus agalactiae</i> infections has been observed in non-pregnant adults. Involvement of the central nervous system in adults remains rare, and its association with spondylodiscitis is exceptional. We report the case of a 65-year-old diabetic patient who presented with acute meningoencephalitis. Microbiological analysis of cerebrospinal fluid and blood cultures identified <i>Streptococcus agalactiae</i>. Despite initial clinical improvement, the patient developed paraparesis and low back pain. Subsequent lumbar imaging revealed L3-L4-L5 spondylodiscitis with epidural and soft tissue abscess. The spinal involvement was presumably caused by the same pathogen. This case highlights the importance of considering the involvement of <i>Streptococcus agalactiae</i> in adult central nervous system infections, especially in the presence of comorbidities.

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Journal
Cureus
Published
2025-08-22
DOI
https://doi.org/10.7759/cureus.90753
Primary Topic
Streptococcal Infections and Treatments
Type
article
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article

Streptococcus agalactiae Meningoencephalitis Revealing Spondylodiscitis in a Diabetic Patient

Youssef El Kamouni, Lamiae Arsalane, Saïd Zouhair, Yousra Boughalem et al.
Cureus
Streptococcal Infections and Treatments
article

Streptococcus agalactiae Meningoencephalitis Revealing Spondylodiscitis in a Diabetic Patient

Youssef El Kamouni, Lamiae Arsalane, Saïd Zouhair, Yousra Boughalem, Doha El Bekkaoui
article en

Abstract

<i>Streptococcus agalactiae</i> is a well-known pathogen responsible for neonatal and postpartum infections. An increase in the incidence of invasive <i>Streptococcus agalactiae</i> infections has been observed in non-pregnant adults. Involvement of the central nervous system in adults remains rare, and its association with spondylodiscitis is exceptional. We report the case of a 65-year-old diabetic patient who presented with acute meningoencephalitis. Microbiological analysis of cerebrospinal fluid and blood cultures identified <i>Streptococcus agalactiae</i>. Despite initial clinical improvement, the patient developed paraparesis and low back pain. Subsequent lumbar imaging revealed L3-L4-L5 spondylodiscitis with epidural and soft tissue abscess. The spinal involvement was presumably caused by the same pathogen. This case highlights the importance of considering the involvement of <i>Streptococcus agalactiae</i> in adult central nervous system infections, especially in the presence of comorbidities.

CureusVol. 17(8)
Cadi Ayyad University (MA), Université Ibn Zohr (MA), Hôpital Militaire Avicenne (MA)
Zero hunger
Openalex Percentile: Top 70%
Streptococcal Infections and Treatments
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Streptococcus agalactiae Meningoencephalitis Revealing Spondylodiscitis in a Diabetic Patient — Youssef El Kamouni, Lamiae Arsalane, et al. · Cureus (2025) | TGRS Research Map | TGRS