Intrinsic capacity, genetic susceptibility, and the risks of metabolic dysfunction–associated steatotic liver disease and cirrhosis
Lower ICs are independently associated with increased risks of MASLD and cirrhosis, regardless of genetic susceptibility. These findings suggest that routine monitoring and early intervention targeting IC may offer a novel strategy to prevent chronic liver disease.
Authors
- Lingfei Guo (ORCID: https://orcid.org/0000-0002-4885-625X)
- Zhuoshuai Liang (ORCID: https://orcid.org/0000-0001-9370-8056)
- Huizhen Jin (ORCID: https://orcid.org/0000-0002-9399-9268)
- Ruofei Li
- Hongrui Zhang (ORCID: https://orcid.org/0009-0001-7383-1927)
- Yawen Liu (ORCID: https://orcid.org/0000-0003-2859-4771)
- Wenhui Gao (ORCID: https://orcid.org/0009-0001-8513-7107)
- Yi Cheng (ORCID: https://orcid.org/0000-0002-7352-3641)
- Xinmeng Hu
Institutions
- Jilin University (CN)
- Shandong Provincial Hospital (CN)
- First Hospital of Jilin University (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- International Journal of Surgery
- Published
- 2025-08-22
- DOI
- https://doi.org/10.1097/js9.0000000000003299
- Citations
- 1
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 1.35