Disseminated intravascular coagulation, associated factors and clinical outcomes among critically Ill septic adults admitted to a tertiary hospital in Ethiopia: A prospective longitudinal study
A quarter of ICU-admitted septic adults developed DIC. The incidence was notably greater by the third day after admission, highlighting the importance of closely monitoring these patients for DIC progression. Elevated AST liver enzyme levels, thrombocytopenia, and prolonged PT are linked to the development of DIC. Changes in these variables could prompt further examination for DIC. The mortality rate did not significantly differ between septic patients with and without DIC. The JAAM score used to diagnose DIC in sepsis patients can serve as a predictor of ICU mortality in sepsis patients with DIC.
Authors
- Elsah Tegene Asefa (ORCID: https://orcid.org/0000-0002-2095-0519)
- Gemeda Abebe (ORCID: https://orcid.org/0000-0002-7172-9136)
- Zeleke Mekonnen (ORCID: https://orcid.org/0000-0003-3418-7291)
- Edosa Kejela
- Girum Tesfaye Kiya (ORCID: https://orcid.org/0000-0001-7858-3793)
- Edosa Tadasa (ORCID: https://orcid.org/0000-0003-1989-2806)
- Gedion Milkias
- Iyasu Demeke
- Aragaw Fiseha
Institutions
- Jimma University (ET)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-08-22
- DOI
- https://doi.org/10.1371/journal.pone.0330842
- Citations
- 2
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 2.71
Funders
- Jimma University