Deinforcement Learning: Rethinking Reward-Based Learning Mechanisms

Conventional reinforcement learning (RL) paradigms, rooted in dopaminergic reward prediction, conflate the absence of reward with punishment. This simplification overlooks pain, a biologically distinct aversive signal with dedicated neural pathways and learning mechanisms. Here we introduce Deinforcement Learning, a framework that integrates pain as an independent computational driver of behavior. Drawing on evidence from neuroscience, psychology, and cognitive science, we show how pain circuits provide rapid, high-salience signals for avoidance and safety, complementing reward-based adaptation. We formalize this perspective in the MaxPain model, which rebalances learning between appetitive and aversive drives. This reconceptualization advances biologically grounded models of decision-making and suggests algorithms with faster convergence, improved robustness, and safer exploration.

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Publication Details

Published
2025-08-22
DOI
https://doi.org/10.31219/osf.io/h98vk_v1
Primary Topic
Neurotransmitter Receptor Influence on Behavior
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article
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article

Deinforcement Learning: Rethinking Reward-Based Learning Mechanisms

Varun Ananth, Jin‐Yong Hong, Chaytan Inman, Marlene Grieskamp
Neurotransmitter Receptor Influence on Behavior
article

Deinforcement Learning: Rethinking Reward-Based Learning Mechanisms

Varun Ananth, Jin‐Yong Hong, Chaytan Inman, Marlene Grieskamp
article en

Abstract

Conventional reinforcement learning (RL) paradigms, rooted in dopaminergic reward prediction, conflate the absence of reward with punishment. This simplification overlooks pain, a biologically distinct aversive signal with dedicated neural pathways and learning mechanisms. Here we introduce Deinforcement Learning, a framework that integrates pain as an independent computational driver of behavior. Drawing on evidence from neuroscience, psychology, and cognitive science, we show how pain circuits provide rapid, high-salience signals for avoidance and safety, complementing reward-based adaptation. We formalize this perspective in the MaxPain model, which rebalances learning between appetitive and aversive drives. This reconceptualization advances biologically grounded models of decision-making and suggests algorithms with faster convergence, improved robustness, and safer exploration.

Massachusetts Institute of Technology (US)
Openalex Percentile: Top 76%
Neurotransmitter Receptor Influence on Behavior
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Deinforcement Learning: Rethinking Reward-Based Learning Mechanisms — Varun Ananth, Jin‐Yong Hong, et al. · (2025) | TGRS Research Map | TGRS