Cedecea davisae infection in a dehisced laparotomy wound: A systematic literature review and case report"

Cedecea davisae is a gram-negative bacterium; an opportunistic pathogen particularly in immunocompromised individuals. Its significance lies in its multidrug resistance. Cases of C.davisae infections are infrequent, making clinical awareness crucial. A comprehensive literature review was performed to gather information on its clinical presentation, diagnostic challenges, and treatment outcomes in previous infections. We present a immunocompromised 65 F who experienced wound dehiscence post laparotomy. Cultures from the wound revealed Cedecea davisae 21 days post-surgery. The identification of C.davisae in this case posed significant challenges due to its unusual occurrence and multidrug resistance, which complicated treatment. This case emphasizes the importance of timely microbiological surveillance and targeted antimicrobial therapy to successfully manage a complex infection. It also underscores the need to consider C.davisae in the differential diagnosis of rare opportunistic infections, particularly in post-surgical contexts. Further studies are essential to enhance understanding of its pathogenicity, transmission, and optimal treatment strategies. • Cedecea Davisae is a sparsely reported but emerging opportunistic pathogen. • This case details a dehisced laparotomy wound by C.Davisae. • Cedecea species share similar resistance profiles to the Serratia species. • Quorum Sensing is suspected to be the mechanism behind its resistance. • Timely, targeted antimicrobial treatment is imperative to elimination of the bacteria.