Nonketotic hyperglycemic hemichorea: white shadows on CT and T1-weighted MRI
Nonketotic hyperglycemic hemichorea (NHH) is a rare movement disorder, most commonly observed in elderly female patients with poorly controlled diabetes. We describe a 55-year-old male patient with diabetes who was admitted due to involuntary movements of the right limbs for five days. CT revealed a hyperdense lesion in the left putamen and caudate nucleus, while MRI showed hyperintensity on T1WI and hypointensity on both T2WI and diffusion-weighted imaging. The patient was treated with oral haloperidol and insulin for blood glucose control, leading to gradual symptom improvement. Follow-up imaging showed resolution of the lesions, correlating with clinical improvement. NHH has characteristic imaging findings and should be differentiated from cerebral hemorrhage, basal ganglia calcification, and hepatic encephalopathy.
Authors
- Libin Liu (ORCID: https://orcid.org/0000-0001-5156-4752)
- Jiezhong Deng (ORCID: https://orcid.org/0000-0002-3637-7585)
- Wenxiao Zhang (ORCID: https://orcid.org/0000-0002-8356-6370)
- Juan‐juan Peng (ORCID: https://orcid.org/0000-0002-9529-4800)
- Zhihui Zhou (ORCID: https://orcid.org/0000-0002-9582-3688)
Institutions
- Zhuhai People's Hospital (CN)
Publication Details
- Journal
- Journal of Radiation Research and Applied Sciences
- Published
- 2025-08-22
- DOI
- https://doi.org/10.1016/j.jrras.2025.101890
- Primary Topic
- Neurological and metabolic disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00