Genetic scissors: A new era in gene therapy

The article gives a brief description of gene therapy, a new technology for treating genetic disorders, and the revolutionary effect of gene editing techniques which include CRISPR-Cas9. The introduction serves as a basis by covering the basics of gene therapy and the revolutionary aspect of genetic scissors as surgical instruments for genetic editing. In a brief overview, gene therapy is explained, which is meant to correct hereditary failing at their source, and subsequently ZFNs (zinc finger nucleases), CRISPR-Cas9 and TALENs are explored. The diverse applications are emphasized in the review, and the paper explores how genetic scissors are utilized in gene repair (correction of mutations which are responsible for diseases such as atherosclerosis, cancer, bone and cartilage repair etc.). It highlights the potential of genetic scissors in changing the therapeutic landscape. The future scope section provides a detailed illustration of the ever-changing capabilities and possibilities of the technology, thereby offering a glimpse of what may be around the next corner. To sum up, the review discusses the ground-breaking role of genetic scissors in gene therapy and stress the necessity of continuous research, ethical standards and collaboration to successfully apply these methods in personalized medicine and healthcare.

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Publication Details

Journal
Journal of Research in Pharmacy
Published
2025-08-22
DOI
https://doi.org/10.12991/jrespharm.1763424
Primary Topic
CRISPR and Genetic Engineering
Type
article
Field-Weighted Citation Impact
0.00
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article

Genetic scissors: A new era in gene therapy

Dhanashree P. Sanap
Journal of Research in Pharmacy
CRISPR and Genetic Engineering
article

Genetic scissors: A new era in gene therapy

Dhanashree P. Sanap
article en

Abstract

The article gives a brief description of gene therapy, a new technology for treating genetic disorders, and the revolutionary effect of gene editing techniques which include CRISPR-Cas9. The introduction serves as a basis by covering the basics of gene therapy and the revolutionary aspect of genetic scissors as surgical instruments for genetic editing. In a brief overview, gene therapy is explained, which is meant to correct hereditary failing at their source, and subsequently ZFNs (zinc finger nucleases), CRISPR-Cas9 and TALENs are explored. The diverse applications are emphasized in the review, and the paper explores how genetic scissors are utilized in gene repair (correction of mutations which are responsible for diseases such as atherosclerosis, cancer, bone and cartilage repair etc.). It highlights the potential of genetic scissors in changing the therapeutic landscape. The future scope section provides a detailed illustration of the ever-changing capabilities and possibilities of the technology, thereby offering a glimpse of what may be around the next corner. To sum up, the review discusses the ground-breaking role of genetic scissors in gene therapy and stress the necessity of continuous research, ethical standards and collaboration to successfully apply these methods in personalized medicine and healthcare.

Journal of Research in PharmacyVol. 29(5)
Bharati Vidyapeeth (Deemed to be University) (IN)
Openalex Percentile: Top 81%
CRISPR and Genetic Engineering
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