Chrysophanol inhibits ischemia/reperfusion-induced neuronal pyroptosis by regulating NRF2/ARE/GSDMD signaling pathway
CHR protects against cerebral I/R injury-induced neuronal loss by regulating NRF2/ARE/GSDMD signaling pathway. Therefore, CHR may be a promising strategy for cerebral I/R injury.
Authors
- Feijian Zeng
- Yufei Wei (ORCID: https://orcid.org/0000-0002-1822-7372)
- Yan Yan (ORCID: https://orcid.org/0000-0002-5917-1475)
- Yong-hua Huang (ORCID: https://orcid.org/0000-0002-6387-0631)
- Yan Wu
- Guihua Huang (ORCID: https://orcid.org/0000-0003-0908-6827)
- Yao Liang (ORCID: https://orcid.org/0009-0000-0908-2071)
Institutions
- Guangxi University (CN)
- The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Tissue and Cell
- Published
- 2025-08-15
- DOI
- https://doi.org/10.1016/j.tice.2025.103082
- Citations
- 2
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.61