Mucus Plugs Correlate with Small Airway Remodeling in Asthma: A Case–Control Study
In asthma, mucus plugs are a prominent and spatially heterogeneous feature within the distal small airways, and are associated with airway wall remodelling and lumen narrowing, making them a key target for improving lung ventilation and patient outcomes.
Authors
- David J. Erle (ORCID: https://orcid.org/0000-0002-2171-0648)
- May Fouadi
- John V. Fahy (ORCID: https://orcid.org/0000-0001-5427-9308)
- Tillie‐Louise Hackett (ORCID: https://orcid.org/0000-0001-7134-3287)
- Aileen Hsieh (ORCID: https://orcid.org/0000-0002-1890-1267)
- Dragoş M. Vasilescu (ORCID: https://orcid.org/0000-0003-3936-4365)
- Maude A. Liegeois (ORCID: https://orcid.org/0000-0001-7015-5970)
- Stacey Ledoux
- Jenna Barker-Mulleder
Institutions
- University of British Columbia Hospital (CA)
- University of British Columbia (CA)
- City College of San Francisco (US)
- University of California, San Francisco (US)
- American Lung Association (US)
- University of California System (US)
- Cardiovascular Institute Hospital (JP)
- St. Paul's Hospital (CA)
- University of San Francisco (US)
Publication Details
- Journal
- American Journal of Respiratory and Critical Care Medicine
- Published
- 2025-08-22
- DOI
- https://doi.org/10.1164/rccm.202501-0310oc
- Citations
- 7
- Primary Topic
- Respiratory and Cough-Related Research
- Type
- article
- Field-Weighted Citation Impact
- 10.63