Mycophenolate mofetil plus methotrexate versus cyclophosphamide with sequential azathioprine for treatment of Takayasu arteritis
Treatment of active TAK with MMF+MTX has more favourable efficacy compared to CYC/AZA. These findings provide evidence to use the combination of MTX and MMF, 2 generally well-tolerated and inexpensive therapies, to treat TAK.
Authors
- Li Luo (ORCID: https://orcid.org/0000-0003-0728-8628)
- Xinwang Duan (ORCID: https://orcid.org/0000-0002-0432-3638)
- Xiaochuan Sun (ORCID: https://orcid.org/0000-0003-3697-6737)
- Xinping Tian (ORCID: https://orcid.org/0000-0002-1511-7952)
- Mengtao Li (ORCID: https://orcid.org/0000-0003-4252-2889)
- Dongyun Yao
- Zhenbiao Wu (ORCID: https://orcid.org/0000-0002-0632-9195)
- Jing Li (ORCID: https://orcid.org/0000-0003-2504-1629)
- Liyun Zhang (ORCID: https://orcid.org/0000-0002-0814-4872)
- Xiuling Zhang (ORCID: https://orcid.org/0000-0003-0818-2366)
- Hongfeng Zhang (ORCID: https://orcid.org/0000-0002-3485-3189)
- Yu Chen (ORCID: https://orcid.org/0000-0002-8931-8079)
- Ying Wang (ORCID: https://orcid.org/0000-0002-4990-8154)
- Yi Zhao (ORCID: https://orcid.org/0000-0001-8926-7446)
- Yahong Wang (ORCID: https://orcid.org/0000-0003-3214-8766)
- Jing Xue (ORCID: https://orcid.org/0000-0001-5902-8444)
- Lili Pan (ORCID: https://orcid.org/0000-0003-2914-078X)
- Peter A. Merkel (ORCID: https://orcid.org/0000-0001-9284-7345)
- Xiaofeng Zeng (ORCID: https://orcid.org/0000-0001-9484-8093)
Institutions
- Nanchang University (CN)
- Capital Medical University (CN)
- Dalian Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
- Second Affiliated Hospital of Nanchang University (CN)
- Jiaozuo University (CN)
- Beijing Anzhen Hospital (CN)
- People's Hospital of Xinjiang Uygur Autonomous Region (CN)
- First Affiliated Hospital of Dalian Medical University (CN)
- Tang Du Hospital (CN)
- Second Affiliated Hospital of Zhejiang University (CN)
- Shanxi Academy of Medical Sciences (CN)
- University of Pennsylvania (US)
Publication Details
- Journal
- Annals of the Rheumatic Diseases
- Published
- 2025-08-22
- DOI
- https://doi.org/10.1016/j.ard.2025.07.018
- Citations
- 3
- Primary Topic
- Vasculitis and related conditions
- Type
- article
- Field-Weighted Citation Impact
- 4.56
Funders
- Peking Union Medical College Hospital