Genome-Wide Cox Regression Analysis Identifies 134 Novel Risk Loci for Disability Development: The Canadian Longitudinal Study on Aging and UK Biobank
This study is among the first genome-wide Cox regression analyses to uncover novel genetic loci and biological pathways involved in disability development in older adults. These findings provide a foundation for predictive modeling and targeted prevention strategies.
Authors
- Xiaojun Wang (ORCID: https://orcid.org/0000-0002-4674-7711)
- Tao Sun (ORCID: https://orcid.org/0000-0003-4447-3005)
- Huiping Zheng
Institutions
- Renmin University of China (CN)
Publication Details
- Journal
- The Journals of Gerontology Series A
- Published
- 2025-08-22
- DOI
- https://doi.org/10.1093/gerona/glaf185
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.00