Nitric oxide increases cross-bridge cycling rate in cardiac muscle but inhibits cycling enhancement due to ß-adrenergic stimulation
Nitric oxide (NO) has a biphasic effect on cardiac contractility, showing a positive inotropy at a low concentration but a negative inotropy at high concentrations. The effect of NO donor S-nitroso- N-acetyl-penicillamine (SNAP) on the kinetics of cr
Authors
- Lynne Turnbull (ORCID: https://orcid.org/0000-0002-9255-9033)
- Joseph F. Y. Hoh (ORCID: https://orcid.org/0000-0002-5085-3349)
- G. H. Rossmanith
Institutions
- The University of Sydney (AU)
- Macquarie University (AU)
Publication Details
- Published
- 2025-08-22
- DOI
- https://doi.org/10.22541/au.175587679.97572793/v1
- Primary Topic
- Cardiovascular and exercise physiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Medical Research Council
- National Health and Medical Research Council