Synergistic Approach to Radicular Cyst Management in an Adolescent: Utilizing Platelet-Rich Fibrin, Demineralized Bone Matrix Xenograft, and Type I Collagen Resorbable Membrane for Optimal Healing

Dentoalveolar injuries can lead to complications like pulpal necrosis, apical periodontitis, and usually radicular cysts, which are common inflammatory odontogenic cysts often triggered by trauma or infection. Radicular cysts are typically asymptomatic but may cause slow, noticeable swelling. This case report details the surgical management of the same in the periapical region of a maxillary incisor in a 12-year-old female patient. The approach included root canal therapy followed by periapical surgery. The cystic lesion was surgically enucleated, and a combination of platelet-rich fibrin (PRF) and demineralized bone matrix (DMBM) xenograft was applied to enhance healing, alongside a type I collagen resorbable membrane. Follow-up evaluations showed the patient was asymptomatic, with significant periapical healing and almost complete bone regeneration observed on radiographs.

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Publication Details

Journal
Cureus
Published
2025-08-14
DOI
https://doi.org/10.7759/cureus.90127
Citations
1
Primary Topic
Oral and Maxillofacial Pathology
Type
article
Field-Weighted Citation Impact
1.79
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article

Synergistic Approach to Radicular Cyst Management in an Adolescent: Utilizing Platelet-Rich Fibrin, Demineralized Bone Matrix Xenograft, and Type I Collagen Resorbable Membrane for Optimal Healing

Rohit Mishra, Varsha Choubey, Debapriya Pradhan, Saurabh Tiwari et al.
1 citations
Cureus
Oral and Maxillofacial Pathology
1.79
article

Synergistic Approach to Radicular Cyst Management in an Adolescent: Utilizing Platelet-Rich Fibrin, Demineralized Bone Matrix Xenograft, and Type I Collagen Resorbable Membrane for Optimal Healing

Rohit Mishra, Varsha Choubey, Debapriya Pradhan, Saurabh Tiwari, Nikita Saini
article en
1 citations

Abstract

Dentoalveolar injuries can lead to complications like pulpal necrosis, apical periodontitis, and usually radicular cysts, which are common inflammatory odontogenic cysts often triggered by trauma or infection. Radicular cysts are typically asymptomatic but may cause slow, noticeable swelling. This case report details the surgical management of the same in the periapical region of a maxillary incisor in a 12-year-old female patient. The approach included root canal therapy followed by periapical surgery. The cystic lesion was surgically enucleated, and a combination of platelet-rich fibrin (PRF) and demineralized bone matrix (DMBM) xenograft was applied to enhance healing, alongside a type I collagen resorbable membrane. Follow-up evaluations showed the patient was asymptomatic, with significant periapical healing and almost complete bone regeneration observed on radiographs.

CureusVol. 17(8)
Govt. Dental College & Hospital (IN)
Openalex Percentile: Top 13%
Oral and Maxillofacial Pathology
1.79
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