Synthesis of carbon nanoparticles from glucose, evaluation of their phenol adsorption capacity, and study their potential as drug delivery systems for treating human pancreatic cancer cells

This research focuses on the synthesis of carbon nanoparticles from glucose through the wet chemical method. The dimensions of the generated particles were evaluated through XRD technology, and the capacity of the synthesized nanoparticles to adsorb phenol particles on their surface was illustrated using UV-VIS and FTIR analysis. The calculation of the loading efficiency (DLE) indicated a remarkably high ratio. The dimensions and morphology of the nanoparticles post-adsorption were assessed through Transmission Electron Microscopy (TEM), revealing the presence of tiny particles within the nanoscale range. To assess the cytotoxic effects on pancreatic cancer cells, various medication doses were prepared utilizing the MTT assay. The results indicate that the generated phenol-loaded nanoparticles exhibit significant potential in eradicating cancer cells.

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Publication Details

Journal
Applied Chemical Engineering
Published
2025-08-15
DOI
https://doi.org/10.59429/ace.v8i3.5702
Primary Topic
Graphene and Nanomaterials Applications
Type
article
Field-Weighted Citation Impact
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article

Synthesis of carbon nanoparticles from glucose, evaluation of their phenol adsorption capacity, and study their potential as drug delivery systems for treating human pancreatic cancer cells

Ghufran Ashour Hammood, Abolfazl Nouri, Amer Hamied Hussein, Maram Ahmed Alaadin et al.
Applied Chemical Engineering
Graphene and Nanomaterials Applications
article

Synthesis of carbon nanoparticles from glucose, evaluation of their phenol adsorption capacity, and study their potential as drug delivery systems for treating human pancreatic cancer cells

Ghufran Ashour Hammood, Abolfazl Nouri, Amer Hamied Hussein, Maram Ahmed Alaadin, Sahar T. Adday
article en

Abstract

This research focuses on the synthesis of carbon nanoparticles from glucose through the wet chemical method. The dimensions of the generated particles were evaluated through XRD technology, and the capacity of the synthesized nanoparticles to adsorb phenol particles on their surface was illustrated using UV-VIS and FTIR analysis. The calculation of the loading efficiency (DLE) indicated a remarkably high ratio. The dimensions and morphology of the nanoparticles post-adsorption were assessed through Transmission Electron Microscopy (TEM), revealing the presence of tiny particles within the nanoscale range. To assess the cytotoxic effects on pancreatic cancer cells, various medication doses were prepared utilizing the MTT assay. The results indicate that the generated phenol-loaded nanoparticles exhibit significant potential in eradicating cancer cells.

Applied Chemical Engineering
Openalex Percentile: Top 79%
Graphene and Nanomaterials Applications
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Synthesis of carbon nanoparticles from glucose, evaluation of their phenol adsorption capacity, and study their potential as drug delivery systems for treating human pancreatic cancer cells — Ghufran Ashour Hammood, Abolfazl Nouri, et al. · Applied Chemical Engineering (2025) | TGRS Research Map | TGRS