Analytical evaluation of C. pictus for its therapeutic properties and antioxidant activity in relation to anticancer potential against selected cancer cell lines

Medicinal plants play an important role in medical care throughout history, including the modern period. Costus pictus, also known as the 'insulin plant,' exhibits numerous bioactivities, including anti-diabetic, antioxidant, anticancer, anti-inflammatory, and hepatoprotective properties. In the present investigation, C. pictus leaves were extracted using ethanol and petroleum ether, and GC-MS analysis revealed 26 and 24 chemical components, respectively. These compounds are used significantly in pharmacology. The antioxidant capabilities of medicinal plants have been studied since they may be in possession of a number of bioactive molecules. It has been demonstrated that antioxidants revert the development of cancer through micromanagement of tumours, and medicinal plants are a rich source of new and powerful antioxidants and anticancer bioactive molecules. In the present study, the anticancer potential of C. pictus leaf extracts in water, ethanol, and petroleum ether against MCF-7 cancer cell lines was evaluated. The MCF-7 cell line was inhibited by all three extracts in a dose-dependent manner. Key words: anti-cancer, anti-inflammatory, pharmacology, GC-MS, MCF-7 cancer cell lines,

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Journal
Journal of Drug Delivery and Therapeutics
Published
2025-08-15
DOI
https://doi.org/10.22270/jddt.v15i8.7338
Primary Topic
Phytochemicals and Antioxidant Activities
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article
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article

Analytical evaluation of C. pictus for its therapeutic properties and antioxidant activity in relation to anticancer potential against selected cancer cell lines

Prerana Pramod Dange, S Padmalatha, Y. L. Ramachandra, D Ashwini et al.
Journal of Drug Delivery and Therapeutics
Phytochemicals and Antioxidant Activities
article

Analytical evaluation of C. pictus for its therapeutic properties and antioxidant activity in relation to anticancer potential against selected cancer cell lines

Prerana Pramod Dange, S Padmalatha, Y. L. Ramachandra, D Ashwini, Pawar Sagar Namdeo
article en

Abstract

Medicinal plants play an important role in medical care throughout history, including the modern period. Costus pictus, also known as the 'insulin plant,' exhibits numerous bioactivities, including anti-diabetic, antioxidant, anticancer, anti-inflammatory, and hepatoprotective properties. In the present investigation, C. pictus leaves were extracted using ethanol and petroleum ether, and GC-MS analysis revealed 26 and 24 chemical components, respectively. These compounds are used significantly in pharmacology. The antioxidant capabilities of medicinal plants have been studied since they may be in possession of a number of bioactive molecules. It has been demonstrated that antioxidants revert the development of cancer through micromanagement of tumours, and medicinal plants are a rich source of new and powerful antioxidants and anticancer bioactive molecules. In the present study, the anticancer potential of C. pictus leaf extracts in water, ethanol, and petroleum ether against MCF-7 cancer cell lines was evaluated. The MCF-7 cell line was inhibited by all three extracts in a dose-dependent manner. Key words: anti-cancer, anti-inflammatory, pharmacology, GC-MS, MCF-7 cancer cell lines,

Journal of Drug Delivery and TherapeuticsVol. 15(8)
Manipal Academy of Higher Education (IN), Kuvempu University (IN)
Kuvempu University
Openalex Percentile: Top 80%
Phytochemicals and Antioxidant Activities
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Analytical evaluation of C. pictus for its therapeutic properties and antioxidant activity in relation to anticancer potential against selected cancer cell lines — Prerana Pramod Dange, S Padmalatha, et al. · Journal of Drug Delivery and Therapeutics (2025) | TGRS Research Map | TGRS